When your organization is actively comparing PACS vendors, the list of things to evaluate can feel endless. Contracts lock you in for years, implementation costs are real, and the wrong PACS vendor selection can set a radiology department back operationally for a long time. This checklist cuts through that complexity with 18 concrete questions, organized by category, so healthcare IT teams have a structured framework for every vendor conversation.
This is not a buyer’s guide for organizations just starting to explore digital imaging. It is for teams already in the evaluation stage: scheduling demos, reviewing proposals, and working toward a final decision.
Architecture and Deployment
The technical foundation of a PACS determines how scalable, resilient, and maintainable it will be for the next five to ten years. Before comparing features, understand how the system is actually built.
Question 1: Is this a true cloud-native architecture, or an on-premise system hosted in the cloud?
Many vendors describe their platform as “cloud-based” when it is actually a legacy on-premise system running on a virtual machine. A true cloud-native PACS uses distributed infrastructure, scales horizontally, and does not require scheduled downtime for upgrades. Ask for specifics: what cloud provider, what services, and how upgrades are delivered.
Question 2: What is the disaster recovery and uptime guarantee?
Request the vendor’s Service Level Agreement for uptime and ask how they handle regional outages. A recovery time objective (RTO) and recovery point objective (RPO) should be documented, not verbal.
Question 3: How is data stored, and where?
Clarify whether images are stored in a single region or across multiple availability zones. For U.S. facilities, data sovereignty matters: confirm that data does not leave U.S. jurisdiction unless your organization explicitly requires cross-border sharing.
Security and Compliance
This section is non-negotiable. A PACS stores protected health information (PHI) at scale. Vendors must be able to demonstrate compliance, not just claim it.
Question 4: What certifications does the vendor hold, and when were they last audited?
Look for SOC 2 Type II, HITRUST CSF, or ISO 27001 certifications. Ask for the date of the most recent audit and whether you can review the executive summary of the audit report.
Question 5: How is PHI encrypted at rest and in transit?
Ask specifically about encryption standards (AES-256 for storage, TLS 1.2 or higher in transit) and whether encryption keys are managed by the vendor or customer. Reviewing the HIPAA technical safeguards framework before this conversation will help you ask more targeted questions.
Question 6: What access controls and audit logging does the system provide?
HIPAA requires audit controls that track who accessed what PHI and when. Confirm that the PACS logs all access events, that the logs are tamper-evident, and that your IT team can run access reports independently.
Integration and Interoperability
A PACS does not operate in isolation. It connects to radiology information systems (RIS), electronic health records (EHR), modalities, and often telehealth platforms. Integration gaps create workflow bottlenecks that outlast the sales conversation.
OmniPACS is built around open standards and deep integration capability, which is why understanding interoperability early in any PACS vendor comparison is so important. A vendor that struggles to answer these questions clearly is likely to struggle during implementation.
Question 7: Which version of DICOM does the system support, and how are DICOM conformance statements made available?
Vendors should be able to provide a DICOM conformance statement that your team can validate against your modality and workstation requirements.
Question 8: How does the system integrate with our EHR?
Whether your organization uses Epic, Cerner, or another platform, ask the vendor to describe the specific integration method: does it use HL7 v2, FHIR R4, or a proprietary connector? Ask for references from other customers using the same EHR.
Question 9: What is the process for routing studies from new modalities?
As facilities add modalities over time, the PACS must be able to receive new DICOM sources without extended engineering work. Understand whether adding a new modality is self-service or requires vendor involvement, and if there is a cost.
For more context on what seamless integration looks like in practice, the guide on RIS PACS system integration covers the architectural and workflow considerations most facilities encounter.
Performance and Reliability
Image retrieval speed and system reliability directly affect radiologist throughput and patient care timelines. Performance benchmarks should be contractual, not anecdotal.
Question 10: What are the documented image retrieval times for your current production customers?
Request actual latency data, not marketing slide benchmarks. A responsible vendor will provide 95th percentile load times for prior image retrieval across facilities similar in size to yours.
Question 11: How does the system perform for remote or distributed sites?
If your organization includes imaging sites across multiple locations, ask how the PACS handles geographic latency. True cloud-native systems often use content delivery or edge caching to reduce load times for remote users.
Question 12: What is the process for planned and unplanned maintenance?
Understand how often the system requires downtime, how much advance notice is provided, and what the downtime procedure is for radiologists who need continuous access. Confirm whether maintenance windows are scheduled around your peak imaging hours.
Pricing and Contracts
Pricing structures in the PACS market vary widely, and it is easy to underestimate the true cost of ownership. A clear read on cloud PACS pricing models before entering these conversations will help you spot structures that look favorable upfront but carry hidden escalation.
Question 13: Is pricing per study, per seat, or per storage volume, and how does it scale?
Each model has different implications as the imaging volume grows. Per-study pricing can become expensive at high volumes. Per-seat pricing penalizes growth in radiology staff. Understand the pricing mechanism and model out costs at 110%, 150%, and 200% of your current study volume.
Question 14: What is the complete list of fees, including implementation, training, data migration, and ongoing support?
The contract price is rarely the full cost. Ask the vendor to provide an all-in cost estimate that includes onboarding, data migration from your existing PACS, user training, and the first year of support. Compare the PACS total cost of ownership across vendors side by side, not just the subscription line item.
Question 15: What are the contract length and exit terms?
Multi-year contracts are common, but the exit clause matters as much as the entry price. Understand what happens if the vendor is acquired, if the product is sunset, or if performance SLAs are consistently missed. Ask whether your data is exportable in standard DICOM format at any time.
Support and Training
The vendor relationship does not end at go-live. Support quality is one of the primary differentiators in long-term customer satisfaction scores across the PACS market.
Teams working through PACS vendor selection consistently report that support responsiveness during critical incidents, not feature lists, determines whether a facility would recommend a vendor to peers. This is where teams at OmniPACS put significant investment: dedicated support, defined escalation paths, and training that goes beyond a self-serve knowledge base. If your organization is new to cloud imaging, the overview of cloud PACS for smaller practices is a useful reference for understanding what good support looks like in practice.
Question 16: What is your support tier structure, and what response times are contractual?
Understand the difference between P1 (system down), P2 (degraded performance), and P3 (general inquiry) response times. Ask whether the contracted response time covers acknowledgment only or active investigation.
Question 17: How is training delivered for radiologists, technologists, and IT staff?
Each user group has different training needs. Radiologists need workflow-specific training on the viewer and worklist. Technologists need modality configuration training. IT staff need administration and integration training. Ask whether initial training is included and what ongoing training costs look like in the event of staff turnover.
Vendor Viability
A PACS contract is a long-term relationship. The vendor’s financial health, roadmap, and market position matter for the life of the agreement.
Question 18: What does your product roadmap look like over the next three years, and how have you invested in AI and cloud integration?
Ask the vendor to share a roadmap, even at a high level. Understand whether they are investing in AI-assisted triage, cloud-native architecture improvements, or additional EHR integrations. Vendors with strong independent satisfaction ratings, such as those that consistently rank well in KLAS performance reviews, tend to maintain focused development cycles and clear support commitments.
Pair the roadmap conversation with a reference check: ask for three customer contacts at organizations similar to yours in size and specialty mix, and call them.
How to Use This PACS Vendor Selection Checklist
Run these 18 questions across every shortlisted vendor before scheduling executive presentations. Assign each response a rating (meets expectations, partially meets, does not meet) and document the evidence. This turns a subjective vendor comparison into a scored matrix your team can defend to leadership.
For teams weighing whether cloud is the right direction at all, the cloud PACS vs on-premise comparison covers the architectural tradeoffs in depth and can inform how you weigh the architecture and pricing questions above.
The goal of this evaluation process is not to find a vendor that answers every question perfectly. It is to find one that answers honestly, backs claims with documentation, and demonstrates the operational maturity to support your facility through go-live and beyond. That combination is harder to find than a feature checklist suggests.
OmniPACS is designed to answer every question in this checklist with documented evidence, not sales-deck slides. If you want to run through this evaluation with a platform built specifically for the complexity of enterprise and multi-site imaging, you can explore OmniPACS Solutions to see how the platform addresses each category above.

Frequently Asked Questions
What is PACS vendor selection and why does it matter?
PACS vendor selection is the process by which a healthcare organization evaluates, compares, and contracts with a vendor to provide its picture archiving and communication system. Because PACS contracts often run five to ten years and the system is central to radiology operations, the selection decision has long-term clinical and financial consequences.
How long does a PACS vendor evaluation typically take?
For enterprise facilities with multiple sites, a thorough evaluation, including demos, reference checks, contract review, and IT validation, typically takes three to six months. Rushing this process is one of the most common causes of post-implementation regret.
What is the most important question to ask a PACS vendor?
There is no single most important question, but the support and contract exit terms tend to reveal the most about a vendor’s confidence in their own product. Vendors with strong platforms rarely resist reference calls or make exit terms difficult.
Should I use KLAS scores as part of my PACS vendor comparison?
KLAS scores are useful as a starting signal, not a final answer. They reflect aggregated user satisfaction across a vendor’s installed base, which may include facilities very different from yours. Use them to narrow the field, then validate with direct reference calls.